Origin
200% Mad is a reaction image expressing violent anger against something, usually showing a character displaying such feeling. The modus operandi behind the picture and its peculiar way of cutting letters to form words were inspired by the Expand Dong meme. It led to an impressive amount of parodies dealing with various reactions and different percentages associated with them.
Origin
Metal Gear Rising: Revengeance is an action hack and slash video game from the Metal Gear franchise that was published from February 2013 for game consoles to January 2014 for PC. In it, the main protagonist, Raiden, has to fight his ways through a series of villains, one of them being Senator Armstrong, well-known for another meme involving nanomachines. In one of the cutscenes, the senator appears shirtless and grinning in anger towards Raiden, glowering at him with redish eyes (shown below in a screenshot from September 2014).
An anonymous user got the idea to mix 200%, corresponding to Raiden’s life bar in the picture, with the grinning face and the letters MAD as a reference to the well-known U mad vernacular (shown below).
Spread
As early as January 26th 2014, the picture was used as a reaction in a 4chan thread from the /v/ (video games) board[1] in which the user asked if there was a way to play Sam, another character from the game, into the main game. Through out 2014, the image would find itself reused on other 4chan boards[2][5], Funnyjunk[3] or Tumblr[4] where it began to be parodied.
Notable examples
[archive from 4chan : may contain NSFW content]